Durable and flexible Waffle outsole helps keep you on the move.
Enhanced Traction
Increased rubber on the outsole for traction and durability.
Cushioned Comfort
Foam midsole and flex grooves provide a cushioned and soft ride.
The video showcases the product in use.The video guides you through product setup.The video compares multiple products.The video shows the product being unpacked. Product Highlights Video Merchant Video
13 reviews for Nike Mens Run Defy Road Running Shoes
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Jerry –
Most comfortable fit
I have been looking for some sneakers for some time and now I am no longer looking. These sneakers feel more comfortable than I expected and look sharp. They are well made and I use them workouts and just walking about. Very happy I got them.
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Buyer –
Good running shoes
Really like it was true to size. Looks good and feels comfortable on my feet.
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Aditya Soni –
Reliable, breathable, and comfortable!
If you’re after a reliable, comfortable running shoe for daily wear, errands, casual runs or walking, the Run Defy is a very solid choice: breathable, cushioned, stylish and good value. If your focus is high mileage, performance runs or rugged conditions, you may want to step up to a more premium model.
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Jen –
Worth the purchase
These shoes are light and comfortable. Fits true to size.
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Margie H. –
Cushy
Let me preface this review with I didn’t buy these shoes for running. I’ve had a pair of Nikes for 15 years and straight up, they’re still comfy and in great shape. So, I bought these. They feel good on my feet, nice and cushy. They are requiring a break in as they’re tight across my toes. They look great! I’m happy and will probably always buy Nike shoes.
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Christina D –
Good shoes.
Very comfortable. Feel nice and supportive while the shoe is soft and flexible.
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Jesse Edgein –
Great Shoes – Great Fit
I run 6 days a week, every week and these shoes are great! They have good support and are very secure on your feet. And at a great price.
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Kindle Customer –
Great running shoe!
These are very comfortable shoes and also look great. I may buy them in other colors for casual wear times.
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laeti –
Parfait rien a dire taille bien
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Sathya –
Wonderful product, great cushioning, soul support and durability. Worth the money spent, brand value and premium shoes
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طلال الشمراني –
أنيق ومريح يناسب أغلب الاوقات، رياضة، خروج مع الاصدقاء، مناسبات غير رسمية إلخ.
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AppropriateSpoon –
To preface this review,I’ve worn solely Nike trainers and running shoes for over 10 years now and I’mpretty heavy footed so I get a new pair every 6 to 9 months. These feel particularly different to put on; they’re a very narrow fit and some of the material choices are more coarse than what I’m used to from Nike. Well made as usual, and they look the part, but I’m really not sold on how they feel to put on and wear.
![Back Bay Slim Running Belt for Women & Men [Fits ALL Phones], Runners Fanny Pack for Men, Money Belt, Running Gear Gift, Waist Bag Workout Gear, iPhone Runner’s Phone Holder Waist Pack](https://fitnfreshco.com/wp-content/uploads/2025/11/819DxJIjQLL._AC_SL1500_.jpg)
Jerry –
Most comfortable fit
I have been looking for some sneakers for some time and now I am no longer looking. These sneakers feel more comfortable than I expected and look sharp. They are well made and I use them workouts and just walking about. Very happy I got them.
Buyer –
Good running shoes
Really like it was true to size. Looks good and feels comfortable on my feet.
Aditya Soni –
Reliable, breathable, and comfortable!
If you’re after a reliable, comfortable running shoe for daily wear, errands, casual runs or walking, the Run Defy is a very solid choice: breathable, cushioned, stylish and good value. If your focus is high mileage, performance runs or rugged conditions, you may want to step up to a more premium model.
Jen –
Worth the purchase
These shoes are light and comfortable. Fits true to size.
Margie H. –
Cushy
Let me preface this review with I didn’t buy these shoes for running. I’ve had a pair of Nikes for 15 years and straight up, they’re still comfy and in great shape. So, I bought these. They feel good on my feet, nice and cushy. They are requiring a break in as they’re tight across my toes. They look great! I’m happy and will probably always buy Nike shoes.
Christina D –
Good shoes.
Very comfortable. Feel nice and supportive while the shoe is soft and flexible.
Jesse Edgein –
Great Shoes – Great Fit
I run 6 days a week, every week and these shoes are great! They have good support and are very secure on your feet. And at a great price.
Kindle Customer –
Great running shoe!
These are very comfortable shoes and also look great. I may buy them in other colors for casual wear times.
laeti –
Parfait rien a dire taille bien
Sathya –
Wonderful product, great cushioning, soul support and durability. Worth the money spent, brand value and premium shoes
طلال الشمراني –
أنيق ومريح يناسب أغلب الاوقات، رياضة، خروج مع الاصدقاء، مناسبات غير رسمية إلخ.
AppropriateSpoon –
To preface this review,I’ve worn solely Nike trainers and running shoes for over 10 years now and I’mpretty heavy footed so I get a new pair every 6 to 9 months. These feel particularly different to put on; they’re a very narrow fit and some of the material choices are more coarse than what I’m used to from Nike. Well made as usual, and they look the part, but I’m really not sold on how they feel to put on and wear.
Durga –
Good sues